Safety Information

Safety you can trust

MEPTIDE has been studied in extensive clinical programs. Review the common side effects, contraindications, warnings and precautions below. This information is not a substitute for professional medical advice.

Common Side Effects

What to expect, and what to do

Most common adverse events are generally mild to moderate and diminish over time.

Nausea

Common

Most common at treatment start; usually diminishes over time.

Vomiting

Common

Mild to moderate in most cases; may occur early in treatment.

Diarrhea

Common

Gastrointestinal side effects often lessen as treatment continues.

Constipation

Common

Ensure adequate hydration and fibre as recommended.

Dyspepsia

Common

Indigestion may occur; talk to your doctor if persistent.

Decreased appetite

Common

Expected effect supporting reduced caloric intake.

Injection-site reactions

Common

Rotate injection sites to minimize local reactions.

Monitor

When should you contact your doctor?

Persistent severe abdominal pain

Severe vomiting

Dehydration

Hypoglycemia when combined with insulin or sulfonylureas

Contraindications

Do not use MEPTIDE if you have any of the following

Hypersensitivity to Tirzepatide or any component of the formulation

Personal or family history of Medullary Thyroid Carcinoma (MTC)

Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2)

Warnings & Precautions

Use cautiously in patients with the following

Pancreatitis — use caution in patients with a history of pancreatitis.

Severe gastrointestinal disease — monitor closely.

Diabetic retinopathy — monitor for changes.

Renal impairment — monitor hydration status.

Gallbladder disease — use with caution.

Hypoglycemia when combined with insulin or sulfonylureas — dose adjustment may be required.

Drug Interactions

Use caution with these medicines

Insulin

Sulfonylureas

Oral medicines requiring rapid gastrointestinal absorption

Dose adjustment of insulin or sulfonylureas may be required when used together.

Special Populations

Use in special populations

Renal Impairment

No routine dose adjustment is generally required; monitor hydration status.

Hepatic Impairment

No clinically meaningful dosage adjustment is generally required.

Elderly

No dose adjustment based solely on age.

Important

Pregnancy, overdose & storage

Pregnancy & Lactation

  • There are insufficient human data regarding use during pregnancy or breastfeeding.
  • MEPTIDE should be used only if the potential benefit outweighs potential risk.
  • Women planning pregnancy should discuss treatment options with their healthcare provider.

Overdosage

Symptoms may include severe nausea, vomiting, gastrointestinal discomfort, and hypoglycemia (particularly with concomitant insulin or sulfonylureas). Management is supportive and symptomatic.

Storage Conditions

  • • Store refrigerated at 2°C–8°C
  • • Do not freeze
  • • Protect from direct light
  • • Keep in original carton until use
  • • Keep out of reach of children
Prescription Medicine

Take the First Step Toward a Healthier Future

MEPTIDE is a prescription medicine. Talk to your doctor to determine whether Tirzepatide is appropriate for your glycemic control and weight-management goals.

Individual results vary. Always follow your healthcare provider's guidance.